Lou Gehrig's disease

noun

Lou Geh·​rig's disease ˌlü-ˈger-igz- 

: amyotrophic lateral sclerosis

Examples of Lou Gehrig's disease in a Sentence

Recent Examples on the Web

Due to his amyotrophic lateral sclerosis, commonly known as Lou Gehrig's disease, Dane has lost use of his right arm. —Kimi Robinson, USA Today, 29 Sep. 2025

The author shared that his decision comes after having to witness the slow death of one of his brothers, who suffered from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. —Vanessa Etienne, PEOPLE, 16 Sep. 2025

That includes research into the treatment and/or prevention of Alzheimer's, various cancers, heart disease, Lou Gehrig's disease and autism. —Sequoia Carrillo, NPR, 3 Sep. 2025

Download it now for the most binge-worthy celeb content, exclusive video clips, astrology updates and more! ALS, also known as Lou Gehrig's disease, is a rare degenerative disease that causes progressive paralysis of the muscles. —Gabrielle Rockson, People.com, 19 June 2025

Word History

Etymology

Lou Gehrig †1941 American baseball player who suffered from the disease

First Known Use

1958, in the meaning defined above

Rhymes for Lou Gehrig's disease

• ferromanganese
• mephistopheles
• ostracods
• abcs
• absentees
• addressees
• adoptees
• allottees
• amputees
• antifreeze
• appellees
• appointees

Medical Definition

Lou Gehrig's disease

noun

Lou Geh·​rig's disease ˌlü-ˌge(ə)r-igz-, -ˌga(ə)r- 

: amyotrophic lateral sclerosis